In this issue, W. Huang et al. review small-molecule quenchers for Förster resonance energy transfer, and C. Cheng et al. summarize work on tailoring bond microenvironments and reaction pathways of single-atom catalysts for efficient water electrolysis. The Minireviews deal with self-healing fibrous membranes (B. Ding et al.) as well as physical and chemical cues at the nano–bio interface for immunomodulation (Y. Zhou et al.). In a Scientific Perspective, Bert Meijer et al. discuss reproducibility in complex supramolecular systems: How can subtle changes make a difference?

In the original research section, P. Hemberger et al. describe the role of ketenes in the induction of the methanol-to-olefins process. S. DeBeer et al. discovered an Fe₆C core in all nitrogenase cofactors. H. Wang et al. used a bioinspired Ti₃C₂T_x MXene-based ionic diode membrane for highly efficient osmotic energy conversion (see picture). S. Yamaguchi et al. investigated olefin–borane interactions in donor–π–accpetor fluorophores that undergo frustrated-Lewis-pair-type reactions.

• Angewandte Chemie 41/2022: Highly Efficient Conversions,
  Angew. Chem. Int. Ed. 2022, 61 (41).