In this issue, Shauna M. Paradine et al. review dienes as versatile substrates for transition-metal-catalyzed reactions. Sebastian J. Pomplun et al. discuss the promising modalities of synthetic peptides for the targeting of disease-related nucleic acids. The Minireviews deal with single-particle and single-molecule characterizations of immobilized enzymes (Eleftheria Diamanti, Fernando López-Gallego), metalloradical catalysis to control the reactivity and selectivity of homolytic radical reactions (Wan-Chen Cindy Lee, X. Peter Zhang), as well as biphasic self-stratifying batteries toward next-generation energy storage (Chenglin Yan et al.).

In the original research section, Honglin Liu et al. describe the acoustic levitation synthesis of ultrahigh-density nucleic acid architectures for specific SERS analysis. Yujie Xiong et al. report abiotic methane production driven by ubiquitous non-Fenton-type reactive oxygen species (see picture). Jennifer Strunk et al. contribute to the structural and electronic understanding of palladium catalysts on nitride and oxide supports. Christoph Jessen and Andreas J. Kornath succeeded in the synthesis and structure elucidation of protonated sulfur dioxide.

• Angewandte Chemie 20/2024: Reactivity and Selectivity,
  Angew. Chem. Int. Ed. 2024, 63 (20).

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