In this issue, J. Rademann et al. review protein-templated fragment ligations. What is the chemistry and biophysics of such reactions, and what is their potential in drug discovery? The Highlight deals with the catalytic desymmetrization by C–H functionalization to solve the chiral methyl problem (D. A. Nagib).

In the Communications section, A. Pich et al. present biofunctional microgel-based fertilizers for controlled delivery of nutrients to plants through their leaves (see picture). G. A. Somorjai et al. provide evidence of structure sensitivity in the Fischer–Tropsch reaction on model nanoparticles by time-resolved transient kinetics. G. Yu et al. present a sustainable redox-flow battery with an aluminum-based deep-eutectic-solvent anolyte. J. M. Slattery et al. succeeded in synthesizing and structurally characterizing a long-term-stable fluoroalkyne.

• Angewandte Chemie 26/2017: Controlled Delivery,
  Angew. Chem. Int. Ed. 2017, 56 (26).