This Belgium based conference is a biannual event which aims to provide coverage of current methods and topics from all areas of organic chemistry.

The BOSS conference attracts speakers of established international standing along with up-and-coming chemists.

The conference also sees the presentation of two prestigious awards:

• The Tetrahedron Chair
• The Janssen Pharmaceutica Prize for Creativity in Organic Synthesis.
  

  

Both awards are accompanied by lectures, with David Macmillan, the recipient of the Tetrahedron Chair, presenting a one-day course on organocatalysis and synthesis. The Janssen Pharmaceutica Prize for Creativity in Organic Synthesis presentation will be given by Eric Jacobsen on “Seeking Fundamental Insights and Practical Reactions: Asymmetric Catalysis as a Synthetic and Mechanistic Tool”.

Plenary Speakers and Selected Publications

Tetrahedron Chair – One-day course
Prof. David MACMILLAN

(PRINCETON UNIVERSITY, Princeton, United States)

• Cycle-Specific Organocascade Catalysis: Application to Olefin Hydroamination, Hydro-oxidation, and Amino-oxidation, and to Natural Product Synthesis
  B. Simmons, A. Walji, D. W. C. MacMillan, Angew. Chem. Int. Ed. 2009, 48, 4349–4353.
  DOI: 10.1002/anie.200900220

Unconventional Reactivity Profiles Induced By Chiral Primary Amine Catalysis
Prof. Paolo MELCHIORRE

(INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA (ICIQ), Tarragona, Spain)

• Organocascade reactions of enones catalyzed by a chiral primary amine
  L.-Y. Wu, G. Bencivenni, M. Mancinelli, A. Mazzanti, G. Bartoli, P. Melchiorre, Angew. Chem. Int. Ed. 2009, 48, 7196–7199.
  DOI: 10.1002/anie.200903280

Recent Advances in Stereoselective Synthesis
Prof. Ilan MAREK

(TECHNION-ISRAEL INSTITUTE OF TECHNOLOGY, Haifa, Israel)

• Convergent Preparation of Enantiomerically Pure Polyalkylated Cyclopropane Derivatives
  A. Abramovitch, L. Fensterbank, M. Malacria, I. Marek, Angew. Chem. Int. Ed. 2008, 47, 6865–6868.
  DOI: 10.1002/anie.200802093

Theming Organic Synthesis for Supramolecular Flatlands
Prof. Davide BONIFAZI

(UNIVERSITY OF NAMUR (FUNDP), Namur, Belgium)

• Supramolecular Chemistry at the Interfaces: Molecular Recognition on Nanopatterned Surfaces
  D. Bonifazi, S. Mohnani, A. Llanes-Pallas, Chem. Eur. J. 2009, 15, 7004–7025.
  DOI: 10.1002/chem.200900900

Minor Enantiomer Recycling – A Strategy for Improving Enantioselectivity
Prof. Christina MOBERG

(KTH SCHOOL OF CHEMICAL SCIENCE AND ENGINEERING, Stockholm, Sweden)

• Reactivity of Pt(0) Complexes in the Oxidative Addition of Aryl Halides and Si B Derivatives
  G. Durieux, M. Gerdin, C. Moberg, A, Jutand, Eur. J. Inorg. Chem. 2008, 27, 4236.
  DOI: 10.1002/ejic.200800285

Directed Evolution of Enzymes: New Biocatalysts for Organic Synthesis
Prof. Nicholas John TURNER

(UNIVERSITY OF MANCHESTER, Manchester, United Kingdom)

• Directed evolution of galactose oxidase: Generation of enantioselective secondary alcohol oxidases
  F. Escalettes, N. Turner, ChemBioChem, 2008, 9, 857–860.
  DOI: 10.1002/cbic.200700689

Palladium- and Nickel-Catalyzed Coupling Reactions of Alkyl Electrophiles
Prof. Gregory C. FU

(MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Cambridge, United States)

• Phosphine‐Catalyzed Stereoselective Synthesis of Highly Functionalized Diquinanes at Room Temperature
  J. Wilson, J. Sun, G. Fu, Angew. Chem. Int. Ed. 2010, 49, 161–163.
  DOI: 10.1002/anie.200905125

Decoding and Engineering Complex Biosynthetic Pathways
Prof. Christian HERTWECK

(LEIBNIZ INSTITUTE FOR NATURAL PRODUCTS, Jena, Germany)

• The Biosynthetic Logic of Polyketide Diversity
  C. Hertweck, Angew. Chem. Int. Ed. 2009, 48, 4688–4716.
  DOI: 10.1002/anie.200806121

Ruthenium Diversity : Alkynes and C-H Bonds in Catalysis
Prof. Pierre DIXNEUF

(UNIVERSITÉ DE RENNES, Rennes, France)

• Ruthenium(II)-Catalyzed Regioselective Synthesis of Allyl Ketones from Alkynes and their Silver(I)-Catalyzed Hydroarylation into -Functionalized Ketones
  M. Zhang, H. Jiang, P. Dixneuf, Adv. Synth. & Catal. 2009, 351, 1488–1494.
  DOI: 10.1002/adsc.200900236

Challenges in Arene-Assembling Chemistry
Prof. Kenichiro ITAMI

(NAGOYA UNIVERSITY, Nagoya, Japan)

• Fe-Catalyzed Oxidative Coupling of Heteroarenes and Methylamines
  M. Ohta, M. Quick, J. Yamaguchi, B. Wünsch, K. Itami, Chem. Asian J. 2009, 4, 1416–1419.
  DOI:10.1002/asia.200900157

Gold-Catalysis: Beyond Enyne Cyclizations
Prof. Antonio M. ECHAVARREN

(INSTITUTE OF CHEMICAL RESEARCH OF CATALONIA (ICIQ), Tarragona, Spain)

• Gold-Catalyzed Reactions of 1,5- and 1,6-Enynes with Carbonyl Compounds: Cycloaddition vs. Metathesis
  Metal-Arene Interactions in Dialkylbiarylphosphane Complexes of Copper, Silver, and Gold
  P. Pérez-Galán, N. Delpont, E. Herrero-Gómez, F. Maseras, A. Echavarren, Chem. Eur. J. 2010, 16, 5324–5332.
  10.1002/chem.200903507

Natural Products: An Opportunity for Discoveries in Chemistry and Biology
Prof. Jef K. DE BRABANDER

(UT SOUTHWESTERN MEDICAL CENTER, Dallas, United States)

• Synthesis of Functionalized Salicylate Esters and Amides by Photochemical Acylation
  O. Soltani, J. De Brabander, Angew. Chem. Int. Ed. 2005, 44, 1696–1699.
  DOI: 10.1002/anie.200462577

Synthetic Biology for Synthetic Chemistry
Prof. Jay. D. KEASLING

(UNIVERSITY OF CALIFORNIA, Berkeley, United States)

• Identification of genes affecting lycopene accumulation in Escherichia coli using a shot-gun method
  M. Kang, Y. Lee, S. Yoon, J. Kim, S. Ock, K. Jung, Y. Shin, J. Keasling, S. Kim, Biotechnol. Bioeng. 2005, 91, 636–642.
  DOI: 10.1002/bit.20539

Utilization of Carbon Dioxide as a Carbon Resource
Prof. Kyoko NOZAKI

(THE UNIVERSITY OF TOKYO, Tokyo, Japan)

• High-Yielding Tandem Hydroformylation/Hydrogenation of a Terminal Olefin to Produce a Linear Alcohol Using a Rh/Ru Dual Catalyst System
  K. Takahashi, M. Yamashita, T. Ichihara, K. Nakano, K. Nozaki, Angew. Chem. Int. Ed. 2010.
  DOI: 10.1002/anie.201001327

Janssen Pharmaceutica Prize for Creativity in Organic Synthesis
Seeking Fundamental Insights and Practical Reactions: Asymmetric Catalysis as a Synthetic and Mechanistic Tool
Prof. Eric JACOBSEN

(HARVARD UNIVERSITY, Cambridge, United States)

• Enantioselective, Thiourea-Catalyzed Intermolecular Addition of Indoles to Cyclic N-Acyl Iminium Ions
  E. Peterson, E. Jacobsen, Angew. Chem. Int. Ed. 2009, 48, 6328-6331.
  DOI: 10.1002/anie.200902420

Decarboxylative Cross-Coupling Reactions: A Modern Strategy for C-C-Bond Formation
Prof. Lukas GOOSSEN

(TECHNISCHE UNIVERSITÄT KAISERSLAUTERN, Kaiserslautern, Germany)

• Decarboxylative Cross-Coupling of Aryl Tosylates with Aromatic Carboxylate Salts
  L. Goossen, N. Rodríguez, P. Lange, C. Linder, Angew. Chem. Int. Ed. 2010, 122, 1129–1132.
  DOI: 10.1002/ange.200905953

Translating Instructions into Function by Self Assembly
Prof. Nicolas WINSSINGER

(UNIVERSITY OF STRASBOURG, Strasbourg, France)

• Molecular Editing of Kinase-Targeting Resorcylic Acid Lactones (RAL): Fluoroenone RAL
  R. Jogireddy, S. Barluenga, N. Winssinger, ChemMedChem, 2010, 5, 670.
  DOI: 10.1002/cmdc.201000047

Chemistry and Biology of Carbohydrates
Prof. Peter H. SEEBERGER

(MAX-PLANCK-INSTITUTE OF COLLOIDS AND INTERFACES, Berlin, Germany)

• Carbohydrate-Mediated Targeting of Antigen to Dendritic Cells Leads to Enhanced Presentation of Antigen to T Cells
  E. Adams, D. Ratner, P. Seeberger, N. Hacohen, ChemBioChem, 2008, 9, 294–303.
  DOI: 10.1002/cbic.200700310

Other Program Highlights

• Poster sessions;
• Exhibition of scientific instruments, books and chemicals;
• Cocktail reception;
• Symposium dinner;
• Excursions to the Caves of Han and the Castle of Lavaux-Ste-Anne or to Val-St-Lambert to see the art of crystal manufacture.

Venue

The Facultés Universitaires Notre-Dame de la Paix (FUNDP Institution or University of Namur) campus is in the center of the city of Namur, the capital of the Wallonia region of Belgium. The campus hosts the symposium in a modern setting yet the University and city boast a rich history.

Location

Namur, located in the south of Belgium, was established as a trading post in the Iron Age and today the evidence of its importance remains in the presence of the Citadel on the site of the original Roman fortification. Namur is also home to a World Heritage Site in the belfry of St Aubin’s Cathedral.

For further tourist information, including restaurants and bars in the area, see:
Namur Tourist Information

Frommers Travel Guide

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• Feel free to visit us at the Wiley stand at the conference!